Immune system and COVID
There is a common reaction between intestinal bacterial and decreased immune function. Certain cells in the lining of the gut spend their lives excreting massive quantities of antibodies into the gut. Researchers at Johns Hopkins are now figuring out how the composition of the gut changes in different diseases, how the body’s immune system interacts with these bacteria and particularly how that relationship may function in disease.
Viral material can interact with other bacterial or viral material. The integrity of Coronavirus particles can be disrupted by surfactin, a bacterial surface molecule that targets other viruses, including that of influenza A. In this light, intestinal microbiota likely influences COVID-19 virulence, while from its side SARS-CoV-2 may affect the intestinal microbiome promoting dysbiosis (gut disruption) and other deleterious consequences. Hence, the integrity of the microbiome can alter the course of SARS-CoV-2 infection, and are likely to play an important, still underscored role in determining individual susceptibility and resilience to COVID-19. Indeed, the vast majority of COVID-19 worst clinical conditions and fatalities develop in subjects with specific risk factors such as aging and the presence of one or more comorbidities, which are intriguingly characterized also by unhealthy microbiome status.
The disruption of the gut bacteria influences immune responses, inflammation, and disease development in the lungs. Although still understood completely, these conditions might count in large amounts with regard to COVID-19 severity. Gut microorganisms are able to regulate mucosal sites distal from the intestine through its metabolites such as short chain fatty acids (SCFAs) that can reach other organsvia the bloodstream to exert immune regulation and induction of immunoglobulins, and anti-inflammatory effects (Zhang D. et al., 2020). A healthy microbiota can counteract respiratory tract infection including the influenza A virus (IAV).
The bacteria between gut/lung axis and seems to impact the lung through blood and when inflammation occurs in the lung, it can affect the gut microbiota as well. The use of pre and probiotics can affect the health and integrity of the gut microbiome.
Have periodontal Issues?
Periodontal pockets are a favorable reservoir for the virus that causes COVID-19, according to research published in Medical Hypotheses (October 2020). There is also some evidence that inflammation caused by periodontal disease could contribute to the severity of a patient’s COVID-19 symptoms. This is because inflammation prompts the release of interleukin-6 (IL-6), which can damage tissue in the lungs and blood vessels. Damage to these body parts can lessen the amount of oxygen a person gets and contribute to COVID-19 progressing faster. COVID-19 joins a number of other diseases worsened by the presence of periodontitis, including diseases of the brain, heart and lungs.
This is why it is so important to eat a healthy diet free of toxins, GMO’s and foods that create inflammation. If you are sensitive to certain foods, I recommend that you avoid them completely. Consume foods that have a variety of colors, fiber and fermentation. This will improve your immune system and help you fight off infections.